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DOI: 10.15690/vsp.v18i3.2032 Background. Nonsteroidal anti-inflammatory drugs safety profile (NSAIDs) is well-studied in clinical trials. Meanwhile, the monitoring of adverse effects (AEs) of this drug class and analysis of AEs structure in pediatrics is essential. Our aim was to study AEs related to NSAIDs in children. Methods. Retrospective analysis of doctor reports about AEs associated with drugs from N02B and M01A [...]

Yu. V. Olefir, B. K. Romanov, R. N. Alyautdin, V. K. Lepakhin,A. E. Krasheninnikov, E. V. Shubnikova The risk-based approach to pharmacovigilance control implemented in Russia since January 1, 2018 increases the responsibility of manufacturers and developers of medicines. The purpose of the work is to assess the system of Express reporting and Periodic reporting [...]

The aim of study was to analyze and investigate the severity of adverse reactions (AR) on drugs used for arterial hypertension treatment in patients living in the Republic of Crimea for the period 2011—2016.Materials and methods. We studied notification cards about AR registered in the regional database of spontaneous messages ARCADe. We analyzed 211 notification cards about AR in [...]