Iron-containing drugs (iron-containing drugs) are a group of drugs containing elemental iron and necessary to replenish the reserve of iron ions in case of iron deficiency and the development of iron deficiency anemia (IDA). The study of the use of drug products in the framework of good pharmacovigilance practice showed an acceptable level of benefit [...]
It is known that pharmacovigilance (FN) performs a socially significant function of ensuring the safety of circulation of medicinal products (MP) both at the stages before registration of a medicinal product (MP) and at the stages after its registration. In the latter case, FN is called post-marketing. In post-marketing PH, pharmaceutical enterprises (FP) are delegated [...]
A significant amount of data from spontaneous messages about drug abuse, detected at the stages of clinical trials and post-registration circulation, as well as the legal requirements of the Rules of Good Pharmacovigilance Practice of the Eurasian Economic Union (EAEU), contribute to the introduction of information technologies in the system for collecting and analyzing messages [...]
According to the WHO rules, monitoring and transfer of information about AD drugs to the VigiBase database can only be carried out by National Pharmacovigilance Centers organized in different countries. Pharmacovigilance documents, pharmacovigilance standard operating procedures (SOPs), master file - all this should be formed according to the same rules. Each country wishing to become [...]
The use of drugs (MP) in practical medicine is inextricably linked with the risk of adverse reactions (AD), which in many cases is caused by an insufficiently established level of drug safety. Studying and ensuring the safety of medicinal products at different stages of the life cycle is an important element of the pharmacovigilance system. [...]
The identification and validation of signals in pediatric practice is very time consuming. The presence of certain problems, such as a shortage of drugs approved for use in pediatrics, a low percentage of reporting of AD messages in children and poor quality of filling in messages, increases the significance of the identified signal. Full-service pharmacovigilance [...]
Выявление и валидация сигналов в педиатрической практике являются очень трудоемкими процессами. Наличие определенных проблем, таких как дефицит лекарственных препаратов, одобренных к применению в педиатрии, низкий процент репортирования сообщений о НР у детей и плохое качество заполнения сообщений, повышает значимость выявленного сигнала. Организации, оказывающие полный спектр услуг по фармаконадзору и формирующие мастер–файл и остальные документы по [...]
The safety of using various drugs in children is one of the main requirements for pharmacotherapy. The study of the effect of drugs (drugs) on the child's body is extremely important, since they can have a negative impact on the growth and formation of a child and further affect the quality of life. Standard operating [...]
The emergence of new effective and safe medicines (drugs) for the prevention and treatment of many diseases and their complications contributes to an increase in life expectancy and, thereby, demographic aging of the world's population as a whole. But, like any drugs, new drugs can cause adverse reactions (AD). In this regard, literature monitoring and [...]
Non-prescription herbal preparations in Russia are traditionally in high demand among the population. In this regard, pharmacovigilance, the audit system, inspection and examination of the safety of medicinal products based on herbal raw materials are of great importance. Among the sedatives of natural origin, widely used in everyday life and in stressful situations, more than [...]
