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Aim. To ground the necessity of taking into account the double-component nature of the phenomenon of poor activity of the population in the system of pharmacovigilance so as to work out the measures, aimed at development of UR reporting. The process of formation of a modern system of pharmacovigilance in Russia with appropriate level of reporting on the cases [...]

This article is devoted to assessing the role of pharmacists in the pharmacovigilance system of the Republic of Kazakhstan. For this, the method of questioning the employees of pharmacy organizations was used, during which the insignificant role of pharmacists in the pharmacovigilance system of the Republic of Kazakhstan was revealed, which is the reason for [...]

Aim: To analyze spontaneous reports of adverse drug reactions in patients with coronary artery disease in the Republic of Crimea for the five-year period from January 2011 to August 2016. Methods: 332 reports of adverse drug reactions in patients with coronary artery disease collected in the “ARCADe” database were analyzed. Out of them, 231 reports on essential drugs affecting the cardiovascular system were [...]

There are a few stages in development of global pharmacovigilance system. These stages include evolution from establishment of first regional institutions such as Food and Drug Administration in USA in 1862 to formation of international systems for adverse drug reactions monitoring (i.e. WHO collaborating center in Sweden Uppsala Monitoring Center); from local regulatory acts, such [...]

A significant role in the development of adverse drug reactions in childhood belongs to ignoring officially approved instructions for medication use. The main medications prescribed «off-label» are cephalosporins; most frequent in pediatric practice are cases of an irrational choice of doses, and also violation of the drug introduction schedule. In order to improve the quality of drug therapy in childhood further development and improvement of the pharmacological surveillance system is necessary.

Matveev A.V., Krasheninnikov A.E., Egorova E.A. Timely high-quality detection, collection and analysis of information on adverse drug reactions is possible only with the presence and active functioningof pharmacovigilance system. One of the most effective methods used to control drug safety is the system of registration and analysis of spontaneous reports. The article is devoted to [...]