A. V. Matveev, E. A. Egorova, A. E. Krasheninnikov, E. I. Konyaeva https://doi.org/10.30895/2312-7821-2021-9-2-95-102 ABSTRACT According to international epidemiological studies, about 80% of women have to use medicinal products during pregnancy, mainly during the first weeks of organogenesis in the case of an unplanned pregnancy, and for the treatment of chronic diseases or acute conditions [...]
A. E. Krasheninnikov, A. V. Matveev, S. D. Marchenko https://doi.org/10.30895/2312-7821-2021-9-3-154-160 ABSTRACT Ensuring the safety of pharmacotherapy is a priority of the national regulatory health policy and is enshrined in the international and federal legislation. Survey of qualified pharmacovigilance experts on current problems in pharmacovigilance is one of the tools for improving the pharmacovigilance system [...]
Retrospective analysis of adverse reactions to penicillin-type antibiotics using the drug problem system methodЕлена Матвеева2021-11-13T20:16:17+03:00
The results of the analysis of ADR cards revealed that amoxicillin-clavulanate and amoxicillin were the "leading" drugs in terms of the frequency of ADR development. It is worth noting the high incidence of ADR development against the background of penicillin use in pediatric patients (from 0 to 18 years) 142 cases.
The Russian pharmacovigilance system faces a spectrum of problems on its way to the formation, including fragmented formulation of conclusions and identification of polymorphic "targets" for subsequent adoption of appropriate management decisions in the field of pharmacovigilance. Typologization of existing problems in the field of pharmacovigilance is a method of reducing the variety of objects under study into several systematized groups for subsequent consolidated analysis of directions to optimize the mechanisms of this system and the possibilities of improving its effectiveness.
Macrolides are one of the groups of antibacterial drugs that are widely used to treat nosocomial infections. This review focuses on the safety of erythromycin. The main attention is paid to the study of prokinetic properties of erythromycin, its cardiotoxicity, and fetotoxicity.